The seizure was made as part of an intelligence led operation.
€1.2 million worth of cocaine was seized by Gardaí on Saturday when two vehicles were stopped and searched on the M3 near Ashbourne in Meath.
Members of the Garda National Drugs and Organised Crime Bureau supported by the Garda National Crime and Security Intelligence Service carried out the stop as part of of an intelligence led operation targeting organised criminality.
The searches that were undertaken with the assistance of the Revenue Customs Service resulted in the discovery and seizure of a quantity of cocaine (subject to analysis) with an estimated street value of €1.2 million.
Two men, aged 35 and 62, were arrested and are currently detained, pursuant to Section 2 of the Criminal Justice (Drug Trafficking) Act, 1996, at Ashbourne Garda Station.
"An Garda Síochána is committed to continuing to disrupt the activities of organised criminals supplying drugs to our communities," Detective Chief Superintendent Angela Willis, who is head of the bureau at GNDOCB, said.
"This seizure of a substantial quantity of cocaine is another example of our relentless efforts to disrupt this supply, enabling us to keep people safe.”